Ewing/PNET characteristic t(11;22) (q24;q12) leading to EWS-FLI1 fusion is encountered in 85% of Ewing Sarcoma/PNET cases. The majority of remaining cases (10-15%) demonstrate fusion of the EWS gene with a second member of the ETS family of genes, namely ERG. The EWS-ERG fusion occurs as a result of chromosomal translocation t(21;22)(q22;q12)
Janet Rowley - Discover of chromosomal translocations leading to disease. Did this at the University of Chicago while working part time and raising her family. Awarded Presidential Medal of Freedom by Barak Obama
Balanced Trans location Support Group - This support group is for men & women struggling with a Balanced Translocation (BT) or an Inversion, both of which are chromosomal abnormalities that often lead to battles with infertility, recurrent miscarriage & pregnancy loss.