Gap Junction (nexus): a specialized intercellular connection between a multitude of animal cell-types; directly connects the cytoplasm of 2 cells, which allows various molecules and ions to pass freely between cells; one gap junction channel is composed of two connexons (hemichannels) which connect across the intercellular space; gap junctions are analogous to the plasmodesmata that join plant cells

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Signaling in Gap Junction The function of Gap Junctions in cell and tissue biology is of utmost importance as Gap-Junctional Intercellular Communication exists in nearly every mammalian cell types.

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Confocal image of a sea squirt heart. The sea squirt heart is a tube made of a single layer of muscle cells. The contractile elements are the long striations stained red and the nuclei are also red. The green spots indicate gap junctions between the cells, which facilitate the conduction of electrical impulses through the heart, thus coordinating its contraction.

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This photo displays three different types of cell junctions. 1. Desmosomes hold cells together (protein to protein). They can be found in heart, uterus, or skin cells. 2. Gap Junctions form links between all cells, allowing cytosol to connect. They are found in cardiac cells. 3. Tight junctions stop fluid and other stuff from passing between cells. They can be found in the urinary tract.

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passief iontransport door kanaaltjes Gap Junctions are channels between cell membranes that allow ions and small molecules to pass directly from one cell to another. These channels are formed by membrane proteins called connexins. Six connexins in the cell membrane form a channel called a connexon. Connexons from two cells form a gap junction. Gap junctions permit electrical signals to pass directly from one cell to another.

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