The skeleton is the most commonly involved organs system in Langerhans cell histiocytosis (LCH) and is by far the most common location for single lesion, often referred to as eosinophilic granuloma (EG) (the terms are used interchangeably in this article). For a general discusion of this disease please refer to the article on Langerhans cell histiocytosis (LCH). Read more: http://radiopaedia.org/articles/skeletal-manifestations-of-langerhans-cell-histiocytosis
Caption: Dendritic and T-cells. Coloured Scanning Electron Micrograph (SEM) of two types of protective cell of the human immune system. A large dendritic or Langerhans cell is seen (at lower right) with a T cell attached (at upper left). Dendritic cells are found in the skin. They recognise foreign proteins (antigens) and ingest them into cytoplasmic Birbeck granules. Antigens are then "processed" and secreted out of the cell, to be dealt with by other immune cells.