Neuromuscular junction. The nerve (in white) transmits its signal to the skeletal muscle (grey tubes) to generate contraction.

Neuromuscular junction. The nerve (in white) transmits its signal to the skeletal muscle (grey tubes) to generate contraction.

Synapse. SEM of a neuromuscular junction showing a motor neuron (orange) terminating on skeletal muscle fibers (pink).

Synapse. SEM of a neuromuscular junction showing a motor neuron (orange) terminating on skeletal muscle fibers (pink).

Neuromuscular Junction Process in Human Nervous System

Neuromuscular Junction Process in Human Nervous System

Myasthenia Gravis. Myasthenia gravis (MG) was first described by Thomas Willis in 1672. It is an acquired autoimmune disease with antibodies against the nicotinic acetylcholine receptor (AChR) at the neuromuscular junction or muscle-specific tyrosine kinase (MuSK). This leads to muscular weakness with easy 'fatiguability', which is worse on exercise and improves with rest. (read more here)

Myasthenia Gravis. Myasthenia gravis (MG) was first described by Thomas Willis in 1672. It is an acquired autoimmune disease with antibodies against the nicotinic acetylcholine receptor (AChR) at the neuromuscular junction or muscle-specific tyrosine kinase (MuSK). This leads to muscular weakness with easy 'fatiguability', which is worse on exercise and improves with rest. (read more here)

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