Mechanisms of atelectasis. A, Collapse of the lung in pneumothorax. B, Compression of the lung by pleural fluid. C, Resorption of the air from alveoli distal to an obstructed bronchus. Obstructive atelectasis is usually focal. Atelectasis of premature infants, which is caused by a deficiency of pulmonary surfactant, is not shown

Mechanisms of atelectasis. A, Collapse of the lung in pneumothorax. B, Compression of the lung by pleural fluid. C, Resorption of the air from alveoli distal to an obstructed bronchus. Obstructive atelectasis is usually focal. Atelectasis of premature infants, which is caused by a deficiency of pulmonary surfactant, is not shown

Mesoporous carbon nanomaterials induced pulmonary surfactant inhibition cytotoxicity inflammation and lung fibrosis

Mesoporous carbon nanomaterials induced pulmonary surfactant inhibition cytotoxicity inflammation and lung fibrosis

Giant liposomes of pulmonary surfactant (40x)  (via Giant liposomes of pulmonary surfactant | 2-photon | Nikon Small World)

Jorge Bernardino de la Serna MEMPHYS - Center for Biomembrane Physics University of Southern Denmark Odense, Denmark Giant liposomes of pulmonary surfactant

Pulmonary Surfactant: The Key to the Evolution of Air Breathing

Pulmonary Surfactant: The Key to the Evolution of Air Breathing

Jorge Bernardino de la Serna MEMPHYS - Center for Biomembrane Physics, Department of Biochemistry and Molecular Biology University of Southern Denmark Odense, Denmark Giant liposomes of pulmonary surfactant Confocal

There are around 150 million alveoli in a human lung. 95% of the alveolar surface area is made of squamous (type I) alveolar cells which allow for gas diffusion between air and blood and 5% of great (type II) alveolar cells which are cuboidal shaped and repair the alveolar epithelium and secrete pulmonary surfactant. Pulmonary surfactant coats the alveoli &small bronchioles and prevents collapsing.

There are around 150 million alveoli in a human lung. 95% of the alveolar surface area is made of squamous (type I) alveolar cells which allow for gas diffusion between air and blood and 5% of great (type II) alveolar cells which are cuboidal shaped and repair the alveolar epithelium and secrete pulmonary surfactant. Pulmonary surfactant coats the alveoli &small bronchioles and prevents collapsing.

Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant. It is the precursor of surfactant and its presence (>0.3) in the amniotic fluid of the newborn indicates fetal lung maturity.

Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant. It is the precursor of surfactant and its presence in the amniotic fluid of the newborn indicates fetal lung maturity.

October 2012 - The EMBO Journal     Giant proteo-liposomes of pulmonary surfactant, material that lines the alveoli of mammals and allows breathing. Each vesicle is 20-50µm in diameter and contains fluorescent dyes highlighting the preferred localization and packing properties of the surfactant lipids and proteins in the membrane. (Credit: Jorge Bernardino de la Serna, EMBOJ) #NPG Nature Publishing Group

October 2012 - The EMBO Journal Giant proteo-liposomes of pulmonary…

The_production_of_pulmonary_surfactant.jpg

Surface tension increases the tendency of the alveoli to collapse. Surfactant decreases the surface tension in the lungs and thus decrease the work of breathing, minimizes collapse and oedema.

Each photomicrography shows a giant liposomes ~20-50µm in diameter comprised of fats and proteins from the surface of the mammalian lung alveoli without any chemical treatment. [Cell Press]

photomicrography of giant liposomes in diameter) comprised of fats and proteins from the surface of the mammalian lung alveoli without any chemical treatment - One of the most ambitious endeavours of synthetic biology is creating “minimal cells”

Pinterest
Search