The economically important Silk Road (red) and spice trade routes (blue) blocked by the Ottoman Empire ca. 1453 with the fall of the Byzantine Empire, spurring exploration motivated initially by the finding of a sea route around Africa and triggering the Age of Discovery.
Calicut, India as rendered in Europe used brutal tactics in India and Southeast Asia in efforts to get in on the spice trade. Image is from Georg Braun and Franz Hogenber's atlas Civitates orbis terrarum.
2 Bohsemeem Spices Trade Cards Weikel & Smith Spice Co Philadelphia Victorian Romantic Charm