9. Get rid of weeds If you want to get rid of weeds in your garden but don’t want to use herbicides. Use Epsom salt. Instead, mix 1 liter of vinegar with 2 tablespoons dish soap and 4 tablespoons of Epsom salts. Stir everything well and pour this into a spray bottle. Spray this solution on weeds. Make sure you don’t spray this on other garden plants.