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Thoracic Outlet Syndrome (TOS) Awareness Page (www.facebook.com/TOS.Awareness) Thoracic Outlet Syndrome (TOS) occurs when the nerves, veins and arteries that pass through the thoracic outlet become compressed. The thoracic outlet is the space between your collarbone (clavicle) and your first rib. This narrow passageway is crowded with blood vessels, nerves and muscles. It is physically debilitating, causes severe pain and in extreme (vascular) cases be fatal.