The Ultimate Itinerary For A Girls’ Weekend Getaway In Florence · Searching for an epic girls' weekend getaway location? Look no further than Florence, Italy. This city straight out of the Italian Renaissance is the perfect place to travel with the girls. This weekend itinerary includes a local's favorite thing to do with her girls- shopping, rooftop drinks, gelato runs, the cutest cappuccino in town, and even a (pink!) Vespa tour!